Turner syndrome dating sites

Turner syndrome dating sites

Elsheikh, D. Dunger, G. Conway, J. It is a result of absence of an X chromosome or the presence of a structurally abnormal X chromosome. Its most consistent clinical features are short stature and ovarian failure. Subjects with TS usually receive intensive medical care during childhood, but the majority are discharged from specialist clinics after the induction of puberty and attainment of final height.

Turner Syndrome: Four Challenges Across the Lifespan

Pediatric management of patients with Turner syndrome focuses on height, frequently resulting in a delay of pubertal induction. The influence of pubertal management on psychosocial adjustment and sex life has not been evaluated in Turner syndrome patients. The objective of the study was to identify the determinants of self-esteem, social adjustment, and initiation of sex life in patients with Turner syndrome, particularly those related to pubertal management.

The study was conducted with a population-based registry of GH-treated patients. Participants included young adult women with Turner syndrome, aged Main Outcome Measures: Low self-esteem was associated with otological involvement and limited sexual experience. Low social adjustment was associated with lower paternal socioeconomic class and an absence of sexual experience. Late age at first kiss or date was associated with cardiac involvement and a lack of spontaneous pubertal development.

Age at first sexual intercourse was related to age at puberty and paternal socioeconomic class. Delayed induction of puberty had a long-lasting effect on sex life. Height and height gain due to GH treatment had no effect on outcomes. Therapeutic interventions altering normal pubertal development in other groups of patients should be reconsidered in light of these findings. The principal features of Turner syndrome are short stature, dysfunctional gonads, cardiac and renal malformations, otological problems leading to hearing impairment, and dysmorphic features of various severities.

Treatment has focused on height 4. GH treatment increases adult height, as shown by a randomized controlled study 5 , confirming earlier reports 6 , 7. However, the height gain is quite variable and its clinical significance is a matter of debate 8. Pubertal development must be induced by drug treatment in girls with Turner syndrome presenting primary ovarian failure. Many studies have considered the effects of this management of puberty on height 9 , 10 , but little is known of its effects on the initiation of sexual activity and its impact on psychosocial functioning.

As for all chronic diseases of childhood, the medical treatment of Turner syndrome should aim to reduce the impact of this condition on psychosocial functioning, in both childhood and adulthood. However, the impact of management on psychosocial outcomes has not been systematically evaluated for Turner syndrome. In a previous study, we observed that health-related quality of life was similar in adult women with Turner syndrome treated with GH in childhood and the general population We identified several components of the disease or consequences of medical management as factors associated with low health-related quality of life scores: In contrast, height or height gain from treatment had no influence Other aspects of psychosocial functioning, such as self-esteem and social adjustment, have not been systematically evaluated in patients with Turner syndrome 12 — It is therefore important to analyze the influence of management options in childhood on these dimensions to help pediatricians make the best choices concerning the management of their patients.

The factors determining the onset of sexuality in humans are poorly characterized, and attention has mostly focused on behavioral, environmental, and psychosocial determinants The timing of puberty affects the onset of sexuality in the general population 16 — Several medical interventions affect the timing of puberty, but their effects on sexual behavior have not been studied 19 , Estrogen replacement in hypogonadal girls has a modest short-term effect on sexual behavior Therefore, Turner syndrome, in which puberty is medically induced in most cases, provides a model to investigate the influence of the timing of puberty on the onset of sexuality.

In this study, we evaluated self-esteem, social adjustment, and sexuality, together with their determinants, in a population-based cohort of Turner syndrome patients treated with GH in France. The design of the study has been described in detail elsewhere 9 , The StaTur cohort includes all patients with a diagnosis of Turner syndrome diagnosed on karyotype analysis who were treated with GH in France during the study period — and were obligatorily registered in the Association France-Hypophyse database.

The Association France-Hypophyse database is nominative, which allowed mailing the questionnaires. A coded identifier was included to medical data exported to the study database and the questionnaires. Data from the questionnaire were entered in the database with the coded identifier but without the personally identifying information, allowing us to keep this confidential information anonymous.

The patients were informed that the database and data analysis were anonymous, although the questionnaires included a coded link to their identity and clinical data. Data relating to features associated with Turner syndrome, growth, and treatments were collected throughout childhood and adolescence 9 , In , a postal questionnaire was sent to all patients older than 18 yr on March 31, It also dealt with demographic characteristics, current health status morbidity, medication , sexual experience, and expectations from GH treatment.

The SEI contains 58 trait-descriptive sentences to which subjects respond by indicating whether the sentences describe them. Scoring is based on a item general subscale and on three 8-item subscales evaluating self-esteem in the social, family, and working areas. The total SEI score is the sum of the four subscales and ranges between 0 and Higher scores indicate higher self-esteem. The SAS-SR questionnaire consists of 54 questions measuring instrumental and communicative role performance over the past 2 wk.

It includes questions on work, social and leisure activities, relationships with family, marital partner, children, and perception of economic functioning. Each item is scored on a 5-point scale with higher scores indicating lower social adjustment. The first, called lifetime sexual experience, classified women as having: The second variable, sexual intercourse experience at the age of 20 yr, took into account the age of participants with its obvious effect on sexual experience.

We quantified the relationships between subscores for the SEI and SAS-SR questionnaires, clinical and demographic characteristics, and sexual experience by means of univariate linear regression. Variables identified as significant in this univariate analysis were then included in a multiple regression model with a backward selection procedure Sexuality was analyzed by means of survival analysis, using first kiss or date or first sexual intercourse as the event considered.

Given that events had not occurred in all women, we used age at time of the survey as censored time for these observations. Survival curves were derived from Kaplan-Meier estimates Multivariate analyses used the Cox proportional hazards regression model 30 , with a backward stepwise selection procedure. The flow chart describing enrollment of patients is presented in Fig.

Details on GH treatments and height outcomes have also been described earlier 9 , Women with Turner syndrome had low SEI scores, particularly for the general and social scales. Pubertal onset was defined as the time of spontaneous breast development or initiation of sex steroid treatment. Pubertal onset was medically induced in patients at Of these patients, 61 required sex steroids later, for pubertal development to complete.

The mean BMI was Given the small number of participants with a partner or children, the corresponding SAS-SR scores were not analyzed. Five of the 38 variables tested were retained in the multivariate models Table 2. Otological abnormalities were associated with low self-esteem in all but one dimension work. Lifetime sexual experience was associated with the overall SEI scale and two of the four SEI subscales, with scores increasing with sexual experience.

Earlier menarche was associated with lower self-esteem for the work dimension only, but age at onset of puberty B2 stage was not a predictor of SEI scores. Several variables were not associated with SEI scores. Predictors of SEI scores were categorized. Results are expressed as absolute scores relative to a reference category set to zero. Results correspond to final multiple regression models explaining each score in columns ; for instance, the mean general score being Eight of the 38 potentially explanatory variables tested were retained in the multivariate models Table 3.

As expected, socioeconomic variables influenced social adjustment. Older participants had lower scores on the family scale. Categorical GHQ score was correlated with all dimensions of social adjustment. Otological involvement had a minor effect. In contrast to what was observed with the SEI scale, increasing sexual experience had no effect, suggesting an all-or-nothing effect of kissing or dating. Interestingly, women over the age of 20 yr at the time of the survey who had never had sexual intercourse or who had begun their sex lives late had higher scores on the work scale.

These variables included adult height or estimated height gain, dysmorphic features, age at menarche, karyotype, cardiac involvement, genital malformations, size of the center, type of estrogen used, and delay to progestin treatment. Results correspond to final multiple regression models explaining each score in columns. Because sexuality was found an important determinant of self-esteem and social adjustment, we constructed Kaplan-Meier curves for the occurrence milestones in the development of sexuality Figs.

In univariate analysis, age at first kiss or date was associated with age at the onset of puberty, induced vs. In the final multivariate Cox model, induced as opposed to spontaneous puberty [hazard ratio HR 0. Age at first kiss or date was not associated with paternal socioeconomic class, dysmorphic features, adult height, or BMI. Age at first kiss or date in women with Turner syndrome.

The rate of event-free survival the proportion of women with no experience of a first kiss or date is shown and subdivided according to predictors significantly associated with events in the final multivariate Cox model see text. A, Kaplan-Meier survival curves according to the type of puberty. B, Kaplan-Meier survival curves according to the presence of cardiac involvement. Age at first sexual intercourse in women with Turner syndrome.

The rate of event-free survival the proportion of women who have not yet had sexual intercourse is shown and subdivided according to predictors significantly associated with events in the final multivariate Cox model see text. A, Kaplan-Meier survival curves according to paternal socioeconomic class. B, Kaplan-Meier survival curves for participants subdivided upper or lower half of the distribution according to age at initiation of puberty, defined as appearance of B2 stage or initiation of estrogen treatment.

In univariate analysis, age at first intercourse was associated with age at onset of puberty and paternal socioeconomic class. In the final multivariate Cox model, lower paternal socioeconomic class [manual worker vs. Age at first intercourse was similarly associated with age at menarche but was not associated with heart involvement, type of puberty, dysmorphic features, adult height, or BMI.

This is the first study to investigate the factors influencing self-esteem, social adjustment, and sexuality in a population-based cohort of women with Turner syndrome. Its results indicate that, in young women with Turner syndrome: Our study has implications for the management of patients with Turner syndrome, pubertal disorders, and, more generally, chronic illnesses of childhood.

Dating & Relationship Seminar Were you able to attend the webinar? If yes, awesome! We hope you had a great experience. If you didn't below. She feels desperate that she's never had a boyfriend or a "real date". . Merry, it's a super awkward stage for all girls, Turner Syndrome or no Turner Syndrome.

My daughter Clare is 18 and a freshman away at college. Over the years she has had crushes on boys and during her junior and senior years of high school had one boy she was very close with whom she wanted to date. This boy never really returned her feelings but she has not been able to move on.

But enough is enough.

Pediatric management of patients with Turner syndrome focuses on height, frequently resulting in a delay of pubertal induction. The influence of pubertal management on psychosocial adjustment and sex life has not been evaluated in Turner syndrome patients. The objective of the study was to identify the determinants of self-esteem, social adjustment, and initiation of sex life in patients with Turner syndrome, particularly those related to pubertal management.

Turner Syndrome

Despite the prevalence of this chromosomal condition, the challenges these women face throughout their lives are not fully understood. This qualitative research study aimed to characterize the subjective experiences of individuals with Turner syndrome throughout their lifespan, to investigate their concerns and obstacles, and to offer insight into the strengths and weaknesses of health care delivery, as they perceived them. Ninety-seven girls and women with TS and 21 parents consented to participate in this interview study. Interviews were semi-structured and open-ended in design. Questions sought to elicit responses relating to existing concerns associated with their condition and positive and negative health care experiences.

Women with Turner Syndrome tell their stories

Turner syndrome is a genetic condition found in females only. It affects about 1 in every 2, girls. Girls who have this condition usually are shorter than average and infertile due to early loss of ovarian function. Usually, a person has 46 chromosomes in each cell, divided into 23 pairs, which includes two sex chromosomes. Half of the chromosomes are inherited from the father and the other half from the mother. The chromosomes contain genes, which determine an individual's characteristics, such as eye color and height. Girls typically have two X chromosomes or XX , but girls with Turner syndrome have only one X chromosome or are missing part of one X chromosome. Turner syndrome is not caused by anything the parents did or did not do. The disorder is a random error in cell division that happens when a parent's reproductive cells are being formed. Girls born with the X condition in only some of their cells have mosaic Turner syndrome.

Or heterotopically to alternative to about turner's syndrome occurs when handing in research paper online now! Uk dating scams female patients, x chromosomes.

Most kids are thrown into puberty whether they like it or not. But Miriam Beit-Aharon, who has a rare genetic disorder, made a choice to enter womanhood. Beit-Aharon has Turner syndrome, a disorder that stunts sexual development and causes infertility in about one in every 2, female births.

A Personal Story: My life with Turner Syndrome

.

.

.

.

.

.

Young Love (Down syndrome and Dating for the First Time)
Related publications